Course details
General
| Faculty | Health Sciences | ||
| Department | Medicine | ||
| Education level | 2nd / Post-graduate | ||
| Course code | PMHRA005 | Trimester | 1 |
| Course title | Female Reproductive Endocrinology | ||
| Independent teaching activities | Hours per week | ECTS | |
| Lectures | 1 | ||
| Exercises | 3 | ||
| Total | 4 | 5 | |
| Coursetype | General knowledge, skill acquiring | ||
| Prerequisite courses | None | ||
| Teaching and assessment language | English | ||
| Course URL | Female Reproductive Endocrinology | ||
Learning objectives
Aim
Upon the completion of this module, the post-graduate student will possess the basic principles of Female Reproductive Endocrinology, and, on an everyday practice level, he/she will be able to understand the rationale of the basic diagnostic and therapeutic approach of cases with relevant disorders.
Knowledge
The participants will possess:
- The basic principles of Reproductive Endocrinology in the female
- The basic principles of Reproductive Endocrinology during the peri-conceptional period
- The basic principles of Reproductive Endocrinology during the peri-menopausal period
Skills
The participants will be able to:
- Apply the basic principles of Female Reproductive Endocrinology on everyday clinical practice
- Evaluate and select the optimal diagnostic procedure, on the basis of sensitivity and specificity
- Prioritize therapeutic modalities, on the basis of cost-benefit ratio
- Transform clinical cases into meaningful clinical queries
- Search for primary and secondary data from reliable sources
- Critically appraise the available data
Syllabus
- Introduction to Female Reproductive Endocrinology
- Menstrual disturbances
- Ovarian failure
- Pituitary tumors
- Hyperprolactinemia
- Functional hypothalamic amenorrhea
- Thyroid disorders
- Polycystic ovary syndrome
- Hyperandogenemia
- Endocrine diseases in pregnancy
- Perimenopause and Menopause
Teaching and learning methods – evaluation
| Teaching methods | Face to face Distance learning |
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| Use of information and communication technologies (ICT) |
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| Module structure | Work Hours per Semester | Activity |
| Lectures | 40 | |
| Exercises (Quiz) | 10 | |
| Exercises (Online discussion fora) | 25 | |
| Exercises (Study relevant papers) | 20 | |
| Final assignment | 30 | |
| Overall work for the course | 125 | |
| Assessment Methods |
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Suggested reading
- Rotterdam ESHRE/ASRM-Sponsored PCOS Consensus Workshop Group.Revised 2003 consensus on diagnostic criteria and long-term health risks related to polycystic ovary syndrome.Fertil Steril. 2004 Jan;81(1):19-25. doi: 10.1016/j.fertnstert.2003.10.004.
- Thessaloniki ESHRE/ASRM-Sponsored PCOS Consensus Workshop Group. Consensus on infertility treatment related to polycystic ovary syndrome. Hum Reprod. 2008 Mar;23(3):462-77. doi: 10.1093/humrep/dem426.
- Garg D, Tal R. The role of AMH in the pathophysiology of polycystic ovarian syndrome. Reprod Biomed Online. 2016 Jul;33(1):15-28. doi: 10.1016/j.rbmo.2016.04.007.
- Boutari C, Pappas PD, Mintziori G, Nigdelis MP, Athanasiadis L, Goulis DG, Mantzoros CS. The effect of underweight on female and male reproduction. 2020 Apr 11;107:154229. doi: 10.1016/j.metabol.2020.154229.
- Mintziori G, Nigdelis MP, Mathew H, Mousiolis A, Goulis DG, Mantzoros CS. The effect of excess body fat on female and male reproduction. 2020 Feb 28:154193. doi: 10.1016/j.metabol.2020.154193.
- Karras S, Paschou SA, Kandaraki E, Anagnostis P, Annweiler C, Tarlatzis BC, Hollis BW, Grant WB, Goulis DG. Hypovitaminosis D in pregnancy in the Mediterranean region: a systematic review. Eur J Clin Nutr. 2016 Mar 2. doi: 10.1038/ejcn.2016.12.
- Abreu AP, Kaiser UB. Pubertal development and regulation. Lancet Diabetes Endocrinol. 2016 Mar;4(3):254-64. doi: 10.1016/S2213-8587(15)00418-0.
- Palioura E, Diamanti-Kandarakis E. Polycystic ovary syndrome (PCOS) and endocrine disrupting chemicals (EDCs). Rev Endocr Metab Disord. 2015 Dec;16(4):365-71. doi: 10.1007/s11154-016-9326-7.
- Anastasiou E, Farmakidis G, Gerede A, Goulis DG, Koukkou E, Kourtis A, Mamopoulos A, Papadimitriou K, Papadopoulos V, Stefos T. Clinical practice guidelines on diabetes mellitus and pregnancy: Ι. Pre-existing type 1 and type 2 diabetes mellitus. Hormones (Athens). 2020 May 15. doi: 10.1007/s42000-020-00192-z.
- Mintziori G, Mousiolis A, Duntas LH, Goulis DG. Evidence for a manifold role of selenium in infertility.Hormones (Athens). 2020 Mar;19(1):55-59. doi: 10.1007/s42000-019-00140-6.
